09:00 Registration (with Coffee & Tea)
10:00 Opening
10:10 Plenary Session
Session 1: Keynote Lecture[Maaszaal]
Chair: Frank Meye (Utrecht)
Roshan Cools (Nijmegen) Role of dopamine in human decision making and cognitive control (45')
11:00 Coffee & Tea
11:30 Parallel Sessions A
Session 2: Control uncertainty and decision-making: impacts on behaviour and mental health[Bloesem]
Chairs: Egbert Hartstra & Roshan Cools (Nijmegen)
Marc Guitart-Masip (Stockholm, Sweden) Quantifying Prior Beliefs About Controllability: a behavioral measure of helplessness (30')
Renée Koolschijn (Nijmegen) The role of environmental richness in resource investment decisions (15')
Filip Grill (Nijmegen) Dopaminergic medication status in Parkinson’s disease is associated with controllability estimation (15')
Yanfang Xia (Nijmegen) “Seeing” controllability and valence: adaptive arousal for metacognitive control under stress (15')
Eliana Vassena (Nijmegen) A computational meta-learning account of effortful persistence (15')
Session 3: Inflammatory pathways in cerebral small vessel disease[Wijnkers]
Chairs: Sebastien Foulquier (Maastricht) & Maximilian Wiesmann (Nijmegen)
Helena Karlström (Stockholm, Sweden) Interplay between vasculature, microglia and neurodegeneration in CADASIL and possible treatment strategies (30')
Tushar Deshpande (Muenster, Germany) Neuroinflammation in mouse models and sporadic cSVD: characterization and comparison (15')
Louise van der Weerd (Leiden) Inflammation in CAA (15')
Ruxue Jia (Nijmegen) Blood-Brain Barrier leakage and neuroinflammation in a translational mouse model of small vessel disease (15')
Sebastien Foulquier (Maastricht) Immune landscape in cSVD: insights from preclinical and clinical data (15')
Session 4: A molecular view on human brain development, function and evolution[Maaszaal]
Chairs: Feline Lindhout (Cambridge, United Kingdom) & Nicky Scheefhals (Nijmegen)
Baptiste Libé-Philippot
(Marseille, France) Elucidating the cellular and molecular divergence of human neurons (30')
Elly
Lewerissa (Nijmegen) Looking at neurodevelopmental disorders through the lens of evolution: a role for the autolysosomal pathway (15')
Feline Lindhout (Cambridge, United Kingdom) Linking human developmental timing and evolution: calcium-mediated tuning of species-specific developmental tempo and neuronal morphology (15')
Frank
Jacobs (Amsterdam) Segmental duplications as an evolutionary source of innovation in brain development (15')
Huib
Mansvelder (Amsterdam) Cortical network specializations supporting adult human cognition (15')
Session 5: From ribosomes to neural networks: translation in brain health and disease[Royal Gala]
Chairs: Max Koppers (Amsterdam) & Ewout Groen (Utrecht)
Sandrine da Cruz (Leuven, Belgium) Uncovering mechanisms of axon/ neuromuscular junction maintenance and demise in ALS (30')
Anne-Sophie Hafner (Nijmegen) Targeting mRNA to neuronal presynaptic compartments. (15')
Oxana Garritsen (Utrecht) Translatome-based subcellular profiling of developing dopaminergic dendron bundles in the substantia nigra (15')
Vivienne Aline Bauer (Amsterdam) Investigating the regulatory role of the endoplasmic reticulum in axonal mRNA localization and translation (15')
Ilaria Signoria (Utrecht) Translation-based biomarker panel for predicting disease progression and treatment response in spinal muscular atrophy (15')
Session 6: Closed loop control of neural interfaces: fundamental neural mechanisms to clinical translation[Pink Lady]
Chairs: Valeria Gazzola (Amsterdam) & Devika Narain (Rotterdam)
Juan Alvaro Gallego (London, United Kingdom) Manifold insights into neural decoding (30')
Valeria Gazzola (Amsterdam) Dynamical social, emotionally loaded, interactions as closed loop systems. Future directions (15')
Julia Berezutskaya (Utrecht) Brain-computer interfaces for communication in paralysis (15')
Yuzhen Qin (Nijmegen) Modeling and control of epileptic dynamics (15')
Dante Muratore (Delft) Large scale high-density active microelectrode arrays (15')
Session 7: Understanding cognitive resilience in aging and Alzheimer’s Disease[Tuin & Waterkers]
Chairs: Harm Krugers & Rik Ossenkoppele (Amsterdam)
Eider Arenaza Urquijo (Barcelona, Spain) Sex and gender differences in cognitive resilience to Alzheimer's Disease: modifiable factors and neurobiological underpinnings (30')
Sven van der Lee (Amsterdam) Genetic risk and genetic resilience, two sides of the same coin? (15')
Amber Boots (Amsterdam) How the prenatal environment may shape dementia risk (15')
Maria Carrigan (Amsterdam) Resilience to Alzheimer’s Disease from a translational perspective (15')
Janssen Kotah (Groningen) Early-life stress influences amyloidosis and the hippocampal synaptic proteome in the APP/PS1 mouse model (15')
13:00 Lunch
14:15 Parallel Sessions B
Session 8: Cortex circuit plasticity and function in relation to natural and reward behavior[Tuin & Waterkers]
Chairs: Frank Meye & Roberto D’Angelo (Utrecht)
Paola Bezzi (Lausanne, Switzerland) Disrupted astrocytic dopamine signaling in the prefrontal cortex triggers compulsive-like behaviors and cognitive deficits (30')
Sergio Conde (Amsterdam) Distinct population dynamics in subregions of the medial prefrontal cortex during action promotion and inhibition. (15')
Roberto D’Angelo (Utrecht) Opposite Effects of Social Stress on prefrontal cortical outputs to the Amygdala and Accumbens - Possible mechanisms for binge-eating - (15')
Bart Jongbloets (Amsterdam) The insula: from cell type identity to probing neuromodulator sensitivity (15')
Clara Hartmann (Amsterdam) Dynamic encoding of goal-directed behavior in prefrontal-hypothalamic circuits during naturalistic exploration (15')
Session 9: The role of glia in brain function and homeostasis[Maaszaal]
Chairs: Peter Meerlo & Susanne Kooistra (Groningen)
Marie-Eve Tremblay (Victoria, Canada) Dynamic interplay between microglia and sleep: outcomes of sleep deprivation and microglial homeostatic alterations (30')
Janssen Kotah (Groningen) Integrating single nucleus RNA sequencing datasets to unravel microglial transcriptional heterogeneity in neurodegenerative diseases (15')
Emmy Hoeksema (Amsterdam) Long term effects of early nutritional interventions with omega-3 dietary fatty acids on amyloid pathology and microglia in a mouse model for Alzheimer’s Disease (15')
Christiaan Huffels (Utrecht) Using a human cortical brain organoid model to study neuron-glia interactions (15')
Aline Mak (Amsterdam) Astro-GRASP: identification of experience- and time-dependent changes in astrocyte-synapse interactions (15')
Session 10: Why play matters: the importance of social play for the development of brain, behaviour and welfare[Royal Gala]
Chairs: E.J. Marijke Achterberg & Heidi Lesscher (Utrecht)
Jackson Ham (Lethbridge, Canada) Growing up in a group: not all rats benefit from playing (15')
E.J. Marijke Achterberg (Utrecht) The role of opioid neurotransmission in social play behaviour (15')
Emel Souiki (Utrecht) Age-dependent effects of risky play on cognitive control over reward in rats (15')
Inonge Reimert (Wageningen) The relation between (social) play behaviour and welfare in pigs (30')
Emmie Koevoets (Utrecht) Play behavior, mental wellbeing and executive functioning in children with and without a chronic condition (15')
Session 11: Powerhouse potential: mitochondrial transfer in health and disease[Wijnkers]
Chairs: Amalia Dolga (Groningen) & Kerensa Broersen (Enschede)
Carla Lopes (Coimbra, Portugal) Mitochondrial extracellular vesicles as modulators of the inflammatory response (30')
Tingting Chen (Groningen) The dual role of indirect mitochondrial transfer in neurodegeneration (15')
Eleonora Aronica (Amsterdam) Unraveling epileptogenesis: the Interplay between mTOR pathway dysregulation, calcium dynamics, and mitochondrial dysfunction (15')
Frank Kruyt (Groningen) Cellular connectivity and mitochondrial transfer in glioblastoma (15')
Minh Danh Anh Luu (Enschede) The importance of mitochondrial calcium regulation in Familial Alzheimer’s disease: insights from iPSC-derived cortical brain organoid and microglial-like cells (15')
Session 12: Computational neuroscience and neurotechnology (CONNECT)[Pink Lady]
Chairs: Mario Negrello (Rotterdam) & Jorge Mejias (Amsterdam)
Wolfgang Maass (Graz, Austria) Problem solving and planning in neural networks (30')
Arezoo Alizadeh (Nijmegen) How the layer-dependent ratio of excitatory to inhibitory cells shapes cortical coding in balanced networks (15')
Renaud Jolivet (Maastricht) On the importance of modelling glial cells (15')
Klaus Linkenkaer Hansen (Amsterdam) The Neurophysiological Biomarker Toolbox (NBT): model-informed EEG biomarkers in a collaborative cloud platform (15')
Lennart Paul Liong Landsmeer (Rotterdam) Memristors to model ion channels (15')
Session 13: Genetic therapies for brain disorders[Bloesem]
Chairs: Ronald Buijsen & Laurie Kerkhof (Leiden)
Karen Anthony (Northampton, United Kingdom) RNA trans-splicing to treat neurodegenerative disorders (30')
Annelot van Esbroeck (Rotterdam) Shooting the messenger: Antisense oligonucleotides as a neurotherapeutic strategy (15')
Bart Klein (Leiden) Developing Axiomer™ ADAR RNA editing platform in the CNS (15')
Alex Garanto (Nijmegen) Use of AAV-Based Strategies for Gene Replacement and Splicing Modulation in the CNS (15')
Marlen Lauffer (Leiden) Therapy development for n-of-1 disorders (15')
15:45 Coffee & Tea
16:00 Plenary Session
Session 14: Keynote Lecture[Maaszaal]
Chair: Roger Adan (Utrecht)
Monique Havermans (London, United Kingdom) How to respond to pressure to phase out animal experimentation in the Netherlands (45')
17:00 Posters & drinks
Session 15: Poster session 1[Waalzaal & Breakout]
18:30 Dinner
20:00 Plenary Session 21:00 Social
Session 16: Top Paper, Thesis & Young Talent Prizes[Maaszaal]Keynote Lecture
Control uncertainty and decision-making: impacts on behaviour and mental health
Inflammatory pathways in cerebral small vessel disease
A molecular view on human brain development, function and evolution
From ribosomes to neural networks: translation in brain health and disease
Closed loop control of neural interfaces: fundamental neural mechanisms to clinical translation
Understanding cognitive resilience in aging and Alzheimer’s Disease
Cortex circuit plasticity and function in relation to natural and reward behavior
The role of glia in brain function and homeostasis
Why play matters: the importance of social play for the development of brain, behaviour and welfare
Powerhouse potential: mitochondrial transfer in health and disease
Computational neuroscience and neurotechnology (CONNECT)
Genetic therapies for brain disorders
Keynote Lecture
Poster session 1
Top Paper, Thesis & Young Talent Prizes
09:00 Registration (with Coffee & Tea)
09:30 Parallel Sessions C
Session 17: Stressed memories and the role of engram neurons, non-neuronal cells and neuromodulators[Maaszaal]
Chairs: Marloes Henckens (Nijmegen) & Harm Krugers (Amsterdam)
Tomas Ryan (Dublin, Ireland) Cold calculation - how engrams effect temperature regulation (30')
Sanne Beerens (Amsterdam) Threat intensity-induced differences in remote memory engram circuits (15')
Sabrina van Heukelum (Nijmegen) Deviations in the trauma memory engram of susceptible mice (15')
Emma Clephas (Nijmegen) Effects of the stress hormone corticosterone on memory inference and its neuronal representation (15')
Jeniffer Sanguino-Gomez (Amsterdam) Glucocorticoid receptors in microglia mediate corticosteroid effects on contextual memory formation (15')
Session 18: Long-term effects of post-acute infection syndromes: a translational perspective[Wijnkers]
Chairs: Jinte Middeldorp (Rijswijk) & Hanneke Willemen (Utrecht)
Marianna Bugiani (Amsterdam) Do viral infections predispose to neurodegeneration? From myths and fears to facts (30')
Denise Visser (Amsterdam) Neuroinflammation and more: PET and MRI in post-COVID patients (15')
Marte Dros (Utrecht) Unravelling the pathophysiological mechanisms of post-acute infection syndromes in adolescents: a multi-omics approach (15')
Juliana Nieuwland (Rijswijk) Persistent neuroinflammation and neuronal loss in a non-human primate model of SARS-CoV-2 infection (15')
Felipe Correa da Silva (Amsterdam) Brain changes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: focus on the stress system and microglia (15')
Session 19: Age related effects of substances of abuse: developmental and translational perspectives[Royal Gala]
Chairs: Karis Colyer-Patel (Rotterdam) & Heidi Lesscher (Utrecht)
Maartje Luijten (Nijmegen) Heavy alcohol consumption during the transition to adulthood (30')
Hanan El Marroun (Rotterdam) How prenatal substance exposure alters brain structure and function (15')
Anaïs Notario Reinoso (Amsterdam) Long-term effects of adolescent cannabinoid receptor activation on adult prefrontal cortex function and behaviour (15')
Sofie van Koppen (Rotterdam) Effects of age of onset of voluntary alcohol consumption on reward sensitivity, impulsivity, and cognitive flexibility in rats (15')
Karis Colyer-Patel (Rotterdam) Age-related effects on the association between alcohol use severity and resting-state fMRI: a rat study comparing adolescent-onset and adult-onset drinking (15')
Session 20: 20,000 microns under the microscope: a journey from the molecular landscape of single synapses to neuronal functioning[Bloesem]
Chairs: Dimitrios Samouil (Utrecht) & Angela Getz (Amsterdam)
Julie Perroy (Montpellier, France) Molecular dynamics at glutamatergic synapses and beyond (30')
Angela Getz (Amsterdam) New tools & techniques for resolving the nanoscale organization and dynamics of endogenous AMPA receptors in intact networks (15')
Dimitrios Samouil (Utrecht) Postsynaptic mGluR – NMDAR crosstalk in shaping synaptic transmission (15')
Anna Galakhova (Amsterdam) From genome to synapse: intelligence-associated genes and HARs converge in human cortical pyramidal cells (15')
Bart Jongbloets (Amsterdam) Visualizing neuromodulator-mediated PKA dynamics in inhibitory neurons (15')
Session 21: Imaging cerebello-cortical networks across development in healthy and clinical populations[Pink Lady]
Chairs: Aleksandra Badura & Ryan Muetzel (Rotterdam)
Muriel Bruchhage (Stavanger, Norway) The importance of cerebellar health (30')
Jana Klaus (Utrecht) Structural cerebellar correlates of verbal and social abilities in autism spectrum disorder are age-dependent (15')
Wietske van der Zwaag (Amsterdam) Cerebellar abnormalities in patients with Multiple sclerosis (15')
Carolin Gaiser (Rotterdam) Child and Adolescent cerebellar development: a population-based perspective (15')
Thomas Jacobs (Rotterdam) Behavioral and brain-wide structural consequences of early life cerebellar lesions - a mouse model study (15')
Session 22: Novel approaches towards transdiagnostic molecular biomarkers for brain disorder[Tuin & Waterkers]
Chairs: Rudy Schreiber (Maastricht) & Igor Magaraggia (Verbania, Italy)
Yang You (Jacksonville, FL, USA) Emerging Role Of Cell-type Specific Extracellular Vesicles In Alzheimer’s Disease: Pathogenesis and Biomarkers (30')
Patty Hoede (Amsterdam) Neuro- and inflammation-related proteins in paired human CSF and CSF-derived extracellular vesicles (15')
Laurence de Nijs (Maastricht) Exploring EV miRNAs as Biomarkers for Psychiatric Disorders (15')
Igor Magaraggia (Verbania, Italy) Harnessing brain-derived extracellular vesicles to support RDoC-based drug development (15')
Jacco Briede (Maastricht) Micro-RNA biomarkers in relation to environmental exposures and psychedelics for CNS disorders (15')
11:00 Coffee & Tea
11:15 Parallel Sessions D
Session 23: The nucleus accumbens: a central hub in metabolic regulation and energy homeostasis[Royal Gala]
Chairs: Astrid van Irsen & Susanne la Fleur (Amsterdam)
Pierre Trifilieff (Bordeaux, France) D1- and D2-MSNs of the nucleus accumbens regulate motivation and food intake in opposite ways: relevance for eating disorders? (30')
Judith Scholing (Nijmegen) The role of low-grade inflammation in effort-based food decision making in obesity - an fMRI study (15')
Wenjie Du (Utrecht) Stress attenuates the excitability of striatohypothalamic pathways: potential consequences for binge eating (15')
Marene Hardonk (Amsterdam) Exercise training and stress resilience: should we look beyond the nucleus accumbens? (15')
Astrid van Irsen (Amsterdam) Chemogenetic activation of D2/A2a-expressing medium spiny neurons in the nucleus accumbens core mirrors the delaying effect of novelty exposure on feeding onset in rats (15')
Session 24: MIMIC-NL: Modeling iPSC - Microglia: Insights & Communication[Maaszaal]
Chairs: Lot de Witte (Nijmegen) & Amalia Dolga (Groningen)
Sally Cowley (Oxford, United Kingdom) Microglia in neurodegenerative disease – what we can learn with iPS cell models (30')
Anne-Marie van Dam (Amsterdam) hiPSC-based model to study microglial functioning in a white versus grey matter like astrocyte environment: relevance for multiple sclerosis? (15')
Kim de Kleijn (Amsterdam) Modelling Alzheimer’s disease characteristics in iPSC-derived 6TF microglia (15')
Dannis van Vuurden (Utrecht) Reawakening microglia and macrophages: modulating the immune response in pediatric high-grade gliomas (15')
Amalia Dolga (Groningen) Air pollution aggravates AD pathology in iPSC-derived microglia exposed to diesel-exhaust particles (15')
Session 25: DNA damage and repair in neurodevelopment and disease[Bloesem]
Chairs: Juliette Kamp (Rotterdam) & Brooke Latour (Nijmegen)
Matthew Ellis (Cambridge, United Kingdom) Uncovering genetic determinants of micronucleus formation (30')
Dick Jaarsma (Rotterdam) Nervous system pathology in nucleotide excision DNA repair-deficiency disorders (15')
Susanne Kooistra (Groningen) Identifying factors driving microglia priming in a mouse model for accelerated aging (15')
Brooke Latour (Nijmegen) The NSL complex promotes neural development by preventing R-loop induced replication stress (15')
Juliette Kamp (Rotterdam) Elucidating DNA break repair in human iPSC-derived neurons (15')
Session 26: Clearing the way to systems neuroscience[Wijnkers]
Chairs: Moritz Negwer (Nijmegen) & Sven Hildebrand (Maastricht)
Hei Ming Lai (Hong Kong, China) Accessible 3D spatial biology for research and clinical use (30')
Moritz Negwer (Nijmegen) Making sense of whole-brain light-sheet image volumes with DELiVR (15')
Sven Hildebrand (Maastricht) Investigating microscopic angioarchitecture in the human visual cortex in 3D with angioMASH tissue clearing and labelling (15')
Sebastien Foulquier (Maastricht) 3D Cerebrovascular architecture in an experimental model of vascular dementia (15')
Zeynep Ilgin Kolabas (Neuherberg, Germany) Unique Insights from Skull Bone Marrow in Health and Disease (15')
Session 27: Bridging scales in brain function: integrating computational and experimental insights into network dynamics and plasticity[Tuin & Waterkers]
Chairs: Anouk Schrantee & Dorien Maas (Amsterdam)
Caroline Lea-Carnall (Manchester, United Kingdom) Modelling and modulating plasticity in healthy and clinical populations (30')
Jorge Mejias (Amsterdam) Digital brain models with cognitive functionalities (15')
Miranda Moore (Amsterdam) Cross-scale correlates of human intelligence: cortical neuronal excitability and network dynamics in the MTG (15')
Dorien Maas (Amsterdam) Multiscale imaging of glioma neurobiology (15')
Anouk Schrantee (Amsterdam) Neuroimaging of functional brain responses to interventions: a multiscale perspective (15')
Session 28: Advancing Amyotrophic Lateral Sclerosis (ALS) research and treatment[Pink Lady]
Chairs: Ling Shan (Amsterdam) & Erik Storkebaum (Nijmegen)
Luc Dupuis (Strasbourg, France) Early non-motor symptoms in amyotrophic lateral sclerosis: a window for therapeutic action? (30')
Erik Storkebaum (Nijmegen) Unraveling the role of the skeletal muscle in ALS associated with FUS mutations (15')
Ling Shan (Amsterdam) Alterations in the histaminergic system in Amyotrophic Lateral Sclerosis: a postmortem study (15')
Henk-Jan Westeneng (Utrecht) Translational imaging in ALS (15')
Suzy Varderidou (Utrecht) Proteomic signature and mesenchymal stem cell-derived extracellular vesicle treatment of iPSC motor neurons from different ALS patient groups (15')
12:45 Lunch
14:00 Plenary Session
Session 29: Keynote Lecture[Maaszaal]
Chair: Kübra Gülmez Karaca (Nijmegen)
Paul Frankland (Toronto, Canada) Critical periods for the emergence of episodic-like memory (45')
14:45 Coffee & Tea
15:00 Parallel Sessions E
Session 30: Cell specificity in the heart of the brain: the hypothalamic paraventricular nucleus[Pink Lady]
Chairs: Andries Kalsbeek & Valentina Rumanova (Amsterdam)
Kristin Eckel-Mahan (Houston, TX, USA) Cell-specific regulation of the circadian clock by BMAL1 in the paraventricular nucleus (45')
Valentina Rumanova (Amsterdam) Using RNAscope and retrograde tracing to benchmark the pre-autonomic neurons of the PVN (15')
Delaram Poormoghadam (Amsterdam) Stress-Specific Activation of Pre-Autonomic and Neuroendocrine Neurons in the PVN (15')
Jari Berkhout (Leiden) Uncovering differential differentiation in vasopressin and oxytocin magnocellular neuron development (15')
Session 31: Lipids as regulators of brain Immunity and repair[Royal Gala]
Chairs: Chun-Xia Yi (Amsterdam) & Jeroen Bogie (Diepenbeek, Belgium)
Jeroen Bogie (Diepenbeek, Belgium) Glial cell lipid processing and recycling in CNS disorders (30')
Chun-Xia Yi (Amsterdam) In-depth immunometabolic profiling of microglia in rats on time-restricted feeding using CENCAT assay (15')
Fleur Mingneau (Diepenbeek, Belgium) 5-lipoxygenase activating protein (FLAP): a novel target to boost the resolution of neuro-inflammation in multiple sclerosis (15')
Han Jiao (Amsterdam) Targeted activation of microglial PPARδ reprograms immunometabolism and enhances insulin sensitivity in diet-induced obesity (15')
Melanie Loix (Diepenbeek, Belgium) UBE3A promotes foam cell formation and counters remyelination by targeting ABCA1 for proteasomal degradation (15')
Session 32: Neural transformation: from adult neural progenitors to brain tumor cells[Wijnkers]
Chairs: Vanessa Donega & Dorien Maas (Amsterdam)
Ana Martin-Villalba (Heidelberg, Germany) Unlocking stemness to treat brain disease and combat aging (30')
Elly Hol (Utrecht) Intermediate filaments: key players in neural progenitors and glioma dynamics (15')
Emma van Bodegraven (Utrecht) Drivers of brain tumor invasion (15')
Daan Kloosterman (Amsterdam) Macrophage-mediated recycling of cholesterol-rich myelin debris fuels glioblastoma malignancy (15')
Mark de Gooijer (Amsterdam) Mitochondrial damage triggers therapy-induced senescence in glioblastoma (15')
Session 33: Neuromodulators make neurons shine: new optical tools to unravel cellular function[Bloesem]
Chairs: Ségolène Bompierre (Nijmegen) & Bart Jongbloets (Amsterdam)
Olivia Masseck (Cologne, Germany) Deciphering the brain's secret code: new tools and approaches (30')
Joachim Goedhart (Amsterdam) Engineering genetically encoded fluorescent probes for fluorescence lifetime imaging microscopy (15')
Isis Alonso-Lozares (Amsterdam) Monitoring real-time dopamine release - Comparison of electrochemical and fluorescent methods (15')
Ségolène Bompierre (Nijmegen) Spatial Protein Kinase A (PKA) dynamics in hippocampal inhibitory neurons and its involvement in inhibitory bouton formation (15')
Emily Willems (Maastricht) The epigenetic signature of phosphodiesterases in mild cognitive impairment and Alzheimer's Disease (15')
Session 34: The importance of sleep for brain function and cognition[Maaszaal]
Chairs: Robbert Havekes (Groningen) & Sylvie Lesuis (Amsterdam)
Carolina Gutierrez Herrera (Bern, Switzerland) The role of thalamo-cortical networks in sleep and cognition: from animal models to stroke patients (30')
Adithya Sarma (Groningen) Restoring access to long-term social memories disrupted by sleep deprivation (15')
Thije Willems (Amsterdam) The role of the AMPAR subunit GluA3 in sleep and memory (15')
Janine Kox (Maastricht) Cognition under pressure: Reversing stress-induced effects on objective sleep measures with Neurexan (15')
Hein van Marle (Amsterdam) Sleep as a window to target traumatic memories (15')
Session 35: A microbiome manifesto: bringing gut-brain axis research from mechanisms to translation[Tuin & Waterkers]
Chairs: Sahar El Aidy & Walter Pirovano (Amsterdam)
Ali Keshavarzian (Chicago, IL, USA) Role of bidirectional Gut-Oral- microbiota-Brain Axis in Parkinson disease (25')
Bas Teusink (Amsterdam) Principles of microbiome structure and function: can we learn from microbial physiology? (15')
Anja Lok (Amsterdam) Mood and the microbes: how to proceed with the patient? (15')
Esther Aarts (Nijmegen) Targeting the gut-brain axis in ageing: the effect of 6 weeks colon-delivered multivitamin supplementation on neurocognition (15')
Panel discussion (20')
16:30 Posters & drinks
Session 36: Poster session 2[Waalzaal & Breakout]
18:00 Closure DNM 25 & poster prizes
Thursday .::. 19 June, 17:00
P1.1 The role of intrinsic activity of basket and stellate cells in cerebellum development
Efstathios Fantidis (Rotterdam)
P1.2 Effects of maternal stress postpartum on mammary gland morphology and macrophage infiltration in mice
Teresa Kuijken (Amsterdam)
P1.3 The AXONER couples translation and secretion machineries for local delivery of axonal transmembrane proteins to regulate axonal development and maintenance
Ha Nguyen (Utrecht)
P1.4 Generation of seven human induced pluripotent stem cell lines with CRISPR/Cas9-mediated deletions in the DMD gene
Kayleigh Putker (Leiden)
P1.5 Spatiotemporal mapping of voltage-gated channels in dendrites of developing human and chimpanzee iPSC-derived neurons reveals species-specific expression patterns
Max Sterling (Nijmegen)
P1.6 Reduction of astrogliosis rescues early synaptic alterations and cognitive decline in a mouse model of Alzheimer's disease by restoring protein synthesis
Cristina Boers Escuder (Amsterdam)
P1.7 Probing mechanisms of temporal lobe seizures and deep brain stimulation in vivo using optical fluorescence voltage imaging
Sukanya Chakraborty (Rotterdam)
P1.8 Dendritic plasticity and EPSP propagation speed in human cortical neurons
Tom Coopmans (Amsterdam)
P1.9 Comparative profiling of synaptic mRNA isoforms in distinct brain regions
Ezgi Daskin (Nijmegen)
P1.10 Computaional potential of exitatory neurons in L3 of the human cortex
Stan Driessens (Amsterdam)
P1.11 A multi-omics approach to explore childhood amnesia
Wouter Droogers (Nijmegen)
P1.12 Spine growth and calcium signaling in pyramidal cell dendrites after two-photon glutamate uncaging
Lotte Herstel (Nijmegen)
P1.13 The role of mechanosensitive ion channel TREK-2 in excitatory presynapse formation on filopodia-shaped nanopillars
Elke Janssen (Nijmegen)
P1.14 Amyloidogenic proteolysis of APP regulates glutamatergic presynaptic function
Akshay Kapadia (Nijmegen)
P1.15 Inhibitory synapse plasticity: unraveling the mechanisms of synaptic pruning in the hippocampus
Troy Kapteijns (Nijmegen)
P1.16 Dysfunction of metabotropic glutamate receptor function in SCA1 human induced pluripotent stem cell-derived neuronal cultures
Laurie Kerkhof (Leiden)
P1.17 Characterization and establishment of iPSC-derived enteric neurons and intestine macrophages to model neuro-intestinal immune axis on-a-chip
Minh Danh Anh Luu (Enschede)
P1.18 Exploring the role of the axon initial segment in action potential generation in human and mouse layer 2/3 pyramidal neurons
Bianca Marin (Amsterdam)
P1.19 Computational modelling of chandelier-cell inhibition of pyramidal neurons
Anastasia Rapti (Amsterdam)
P1.20 Exploring how different perisynaptic astrocytic process (PAP) proteins affect astrocyte-neuron interaction
Tessa Tuinzaad (Amsterdam)
P1.21 The molecular dynamics of the synapse during learning and plasticity
Stanley Van (Nijmegen)
P1.22 The role of myosins in the maintenance of the cisternal organelle in the axon initial segment
Martijn Zegelaar (Eindhoven)
P1.23 Unraveling the molecular mechanism of frontotemporal dementia
Lars Aartsen (Delft)
P1.24 Lysosomal acidification in a hiPSC model for Parkinson’s disease
Neslihan Akbulut (Nijmegen)
P1.25 Illuminating early white matter changes in cerebral small vessel disease: a polarized light imaging study
Floor Arentz (Nijmegen)
P1.26 Analysis of activity-regulated gene expression in a DNA-repair deficient mouse model
Zoë Bartalits (Rotterdam)
P1.27 Decoding EV-miRNA-regulated neurodegenerative pathways in the aftermath of COVID-19
Gunjan Bawne (Rijswijk)
P1.28 Presynaptic protein Brinp2 controls neuromodulatory receptor availability and mitigates age-related decline in synaptic plasticity
Marinka Brouwer (Leuven, Belgium)
P1.29 From RRMS to SPMS: unraveling the epigenetic signature of Tregs and their role in remyelination
Sarah Chenine (Diepenbeek, Belgium)
P1.30 Investigating sex differences in the acquisition of a touchscreen-based Location Discrimination task in an Alzheimer’s Disease mouse model
Luna Hall (Groningen)
P1.31 Investigating LRP10-mediated pathogenic pathways in Lewy Body Diseases using iPS derived model systems
Fares Khazneh (Rotterdam)
P1.32 A new mouse model for the leukodystrophy MLC based on a rare variant in the orphan receptor GPRC5B
Freya Kirwan (Amsterdam)
P1.33 Bacteriophages detecting amyloid beta oligomers can serve as a diagnostic tool in Alzheimer’s disease
Lucas Lumeij (Amsterdam)
P1.34 The ferric fate of neurons: synuclein and ferroptosis in Parkinson’s Disease
Irona Mostafa (Groningen)
P1.35 Microglia heterogeneity during aging in nonhuman primates
Erik Nutma (Rijswijk)
P1.36 Microglia exhibit different morphological states depending on their proximity to engram neurons and amyloid plaques in APP/PS1 mice
Niek Renckens (Amsterdam)
P1.37 CRISPR/Cas9-mediated deletion of astrocytic GFAP and Vimentin to reduce astrogliosis in AD mice
Naz Simsek (Amsterdam)
P1.38 DARS2 compound heterozygosity in the UK biobank. Searching for evidence of subclinical phenotypic effects in carriers of DARS2 variants
Jack Smith (Amsterdam)
P1.39 Identification of RNA-templated DNA repair in iPSC-derived neurons
Pablo Sprunken (Breda)
P1.40 Investigating early alpha-synuclein dysfunctions: insights from a patient-derived model towards understanding Parkinson’s disease
Marloes Thijs (Nijmegen)
P1.41 Microglia morphologic changes based on local microenvironment in 4M and 6M old APP/PS1 Arc::dVenus mice
Desirée van Dam (Amsterdam)
P1.42 Early alpha-synuclein oligomerization and synaptic dysfunction in a human model of Parkinson’s disease
Eline van Hugte (Nijmegen)
P1.43 Epileptiform activity across the Alzheimer’s disease continuum: findings from routine magnetoencephalography
Anne van Nifterick (Amsterdam)
P1.44 Specific inhibition of TNFR1 as a potential therapy for Alzheimer’s disease
Kylan van Vliet (Groningen)
P1.45 Targeting microglial glucocorticoid receptors to mitigate AD pathology
Tamara Versluis (Amsterdam)
P1.46 Novel APP p.V742L variant in a patient with cerebral ischaemic strokes interferes with critical functions of its intracellular domain
Bas Voesenek (Leiden)
P1.47 Investigating microglial phagocytosis in the local microenvironment in Alzheimer’s disease
Emma Witzier (Amsterdam)
P1.48 Menopause-associated neuroinflammation in female ovariectomized mice: implications for Alzheimer’s disease
Maria Zernova (Groningen)
P1.49 Piecing Cornelia de Lange syndrom together: one mosaic brain organoid at a time
Marieke Alzeer (Rotterdam)
P1.50 Investigating the activity of UBE3A in Neurodevelopmental disorders: a multi-model approach
Antonia Belecha (Rotterdam)
P1.51 Toward a deeper structural and cellular understanding of CAMK2G
Angelica Casotto (Delft)
P1.52 SETD1B variants drive neurodevelopmental disorder and epilepsy: insights from patient-derived iPSC models
Iris Cornelissen (Rotterdam)
P1.53 Studying the effect of the CAMK2B-p.P139L patient mutation in neuronal network development using both mouse primary- and human iPSC-derived neurons in vitro
Anouk Heuvelmans (Rotterdam)
P1.54 Unraveling the epigenetic landscape of mosaic Cornelia de Lange Syndrome: insights from iPSC-derived cortical brain organoids
Amber Hof (Rotterdam)
P1.55 Simulating the perinatal testosterone surge in human iPSC-derived neuronal excitatory-inhibitory cultures to elucidate sex-specific vulnerabilities to autism
Sam de Kater (Nijmegen)
P1.56 Building a valid stem cell model for SCN1A-related epilepsies
Nikki Kolsters (Nijmegen)
P1.57 Functional EEG markers for indicating seizure risk and anti-seizure medication efficacy
Georgii Krivoshein (Leiden)
P1.58 Unraveling the role of pik3cd GOF mutation on CNS and behavior
Devika Kurup (Rotterdam)
P1.59 The disruptive effects of methylphenidate treatment on circadian rhythm in adult female zebrafish and epigenetic transmission of its negative effects to offspring
Ayse Reyyan Kutan Basci (Ankara, Turkey)
P1.60 Developing a platform to screen antisense oligonucleotides for personalized therapy in rare neurodevelopmental disorders
Nadine Maas (Rotterdam)
P1.61 Selective reactivation of Scn1a gene in GABAergic interneurons to explore symptomatic reversibility in Dravet Syndrome
Martina Mainardi (Milan, Italy)
P1.62 AI tools to explore the effect of MLC patient mutations on GPRC5B dimerization
Rosa Randoe (Amsterdam)
P1.63 Local and distal projections of VTA and SN PAX5-expressing cells in adult mice
Maria Roa Oyaga (Rotterdam)
P1.64 Analysis of genetic overlap between inborn errors of immunity and neurodevelopmental disorders
Ines Serra (Rotterdam)
P1.65 Elucidating the role of Shank2 in neuronal polarity
Vasiliki Theodorou (Amsterdam)
P1.66 Development of an iPSC-based platform to assess therapeutic antisense oligonucleotide strategies for Costello Syndrome
Dana Vervloet (Rotterdam)
P1.67 Neurobiological consequences of chronic sleep restriction: effects on neuronal plasticity and BDNF signalling
Nienke de Vries (Groningen)
P1.68 The role of childhood trauma on subjective and physiological alcohol cue reactivity: a gender-based study
Maria Eleni Goureli (Amsterdam)
P1.69 How cortisol may contribute to the development of anxiety disorders: construction of an adverse outcome pathway network
Elise Heesbeen (Utrecht)
P1.70 Sex differences in the impact of stress exposure on the hypothalamic gene expression during early life and adulthood
Selma Heijdra (Amsterdam)
P1.71 Gender differences in daily life assessments of alcohol cue-induced and stress-induced craving and alcohol consumption in hazardous drinkers
Luise Laser (Amsterdam)
P1.72 Modelling perinatal brain hypoxia using human iPSC- derived adherent cortical organoids
Maria Madejon (Rotterdam)
P1.73 Impact of prenatal stress on maternal brain: focus on microglia and immune function
Anna Sancho Balsells (Amsterdam)
P1.74 Enhancing positive schemas with tDCS: a pilot study
Angeliki Sideri (NIjmegen)
P1.75 Brain activity and connections in response to mate song in higher auditory areas and social behaviour network in female zebra finches (Taeniopygia guttata), in the context of pair bonding
Teije Bonsema (Groningen)
P1.76 What does the fruitfly see?
Ivo van Haastert (Groningen)
P1.77 Unraveling female auditory perception through behavioral ecology-oriented neuroscience
Andrés Viñas Martínez (Groningen)
P1.78 Cerebellar control of context-dependent motor timing
Ilse Klinkhamer (Delft)
P1.79 Deciphering movement: shaping the behavior of Purkinje cell subpopulations
Henrietta Serpescu (Rotterdam)
P1.80 Exploring instant transcranial electrical stimulation effects on brain-wide functional connectivity using simultaneous MEG
Annel Koomen (Amsterdam)
P1.81 Waking experience during sleep deprivation shapes neural activity in the prefrontal cortex
Marina Ocaña Prieto (Groningen)
P1.82 The effect of light at night on sleep architecture and BDNF
Alessia Palazzo (Groningen)
P1.83 Testing brexpiprazole administration on socio-aggressive behavior in wild-type rats
Pablo Puértolas Domínguez (Groningen)
P1.84 Somatosensory layer 5 pyramidal tract neurons efficiently encode diverse whisker stimuli via broad and variable receptive fields
Sofja Solovjova (Amsterdam)
P1.85 The effect of light at night on sleep architecture and BDNF
Anna van Beek (Groningen)
P1.86 Mice emit unique high frequency vocalizations during tickling
Max van der Doe (Amsterdam)
P1.87 The role of dopamine transporter availability in alcohol addiction and its potential to predict treatment response to bupropion and aripiprazole in rats
Emile Zweistra (Nijmegen)
P1.88 Whole-brain tracing of shock observation engram neurons in the anterior cingulate cortex
Ákos Babiczky (Amsterdam)
P1.89 Early life stress and living in a complex environment: effects on social hierarchy, stress coping, and brain plasticity in mice
Elisabeth Bouwman (Amsterdam)
P1.90 The role of Cadm2 in alcohol consumption and relapse behaviour
Marijke Lammers (Amsterdam)
P1.91 Mapping the dopamine receptor 1-expressing efferent neurons from the central, medial and basolateral amygdala
Roberta Tandari (Amsterdam)
P1.92 How motivational mechanisms shape real-life well-being: a large scale study of stress vulnerability
Bilge Uysal (Nijmegen)
P1.93 Differences in excitability of ventral hippocampus projecting serotonergic cells underlie sex-dependent modulation of anxiety levels
Suzanne van der Veldt (Groningen)
P1.94 The role of ovarian hormones on time-of-day effects on cognition in women with late chronotype
Zilla Bosman (Groningen)
P1.95 The age-dependent impact of juvenile risky play on cognitive control over behaviour in male rats
Jason Getty (Utrecht)
P1.96 Intermediate hubs connecting cerebellar nuclei with basal forebrain
Tom Klumperman (Rotterdam)
P1.97 Anterior cingulate to prelimbic cortex projections modulate remote retrieval of conditioned threat memory
Lieke Steijvers (Amsterdam)
P1.98 Ethical perspectives in a moral trade-off system: examining moral decision-making, preference consistency, and predictors of moral phenotypes in military and civilian populations
Lukas van Herk (Utrecht)
P1.99 Sleep spindles predict post-sleep decoding accuracy of visual working memory representations
Sophia Wilhelm (Groningen)
P1.100 Theta and Alpha EEG rhythms associated with sex and with working memory in individuals with amnestic Mild Cognitive Impairment
Zhenyu Zhang (Groningen)
P1.101 From brain to cloaca - an unexpected journey: AAVs shedding dynamics following CNS administration in birds
Massimiliano Coscia (Groningen)
P1.102 Altered periaqueductal gray functional connectivity in overactive bladder patients: a resting-state functional MRI study using clustering analysis
Susana Fernandez Chadily (Maastricht)
P1.103 Spatiotemporal mass spectrometry of biosynthetic Neuroligin-1 elucidates its trafficking and destination interactome
Noortje Kersten (Utrecht)
P1.104 Mapping the human thalamic reticular nucleus (TRN) by means of an ultra-high field 7T MRI: toward a probabilistic atlas
Zuzanna Kotwicka (Maastricht)
P1.105 Behind the signals: practical insights to refine EEG quality and reliability in rodent studies
Roy Meijer (Groningen)
P1.106 The BPRC Nonhuman Primate Brain Bank (NHPBB) initiative for aging and disease research
Jinte Middeldorp (Rijswijk)
P1.107 Ptrap: a comprehensive pipeline for quantitative analysis of optical images
Teresa Niederländer (Rotterdam)
P1.108 GOATEA: gene set enrichment analysis with interactive visualization
Maurits Unkel (Rotterdam)
P1.109 Dissecting the mechanisms of deep brain stimulation and parkinson's disease using optical voltage imaging
Maxime van Veghel (Rotterdam)
P1.110 Comparing signal quality in rodent fMRI across awake and anaesthetised imaging protocols
Eline Vansina (Amsterdam)
P1.111 Of mice, men, and naked mole-rats: proteostasis mechanisms across lifespans
Sharon Gloudemans (Nijmegen)
P1.112 Oscillatory network dynamics and the regenerative nature of memory: toward a biologically grounded theory of intelligence
Mario Negrello (Rotterdam)
Friday .::. 20 June, 16:30
P2.1 Infant colic and behavioral problems from childhood to adolescence – moderation by maternal childhood trauma and attachment style
Asia Latini (Nijmegen)
P2.2 Studying the role of Semaphorin-6A reverse signaling in cortical neuron migration
Ruben van Amerom (Utrecht)
P2.3 Glial development and axonal interactions in neocortical organotypic slice cultures
Viktor Al Naqib (Amsterdam)
P2.4 Impact of hypercortisolaemia on neurons and glial cells in human hypothalamus of patients with cushing’s syndrome
Karima Allach (Amsterdam)
P2.5 Human iPSC- derived microglia integration in 2D neural cultures and Adherent Cortical Organoids
Sakshi Bansal (Rotterdam)
P2.6 The intracellular molecular mechanisms underlying plasticity of GluA3-containing AMPA receptors
Iris Berden (Amsterdam)
P2.7 Chronic amyloid-β oligomer exposure may drive microglial activation in early Alzheimer’s disease model
Simão Bettencourt (Nijmegen)
P2.8 Development of fluorescent activated tripartite synaptosome sorting
Thomas Blok (Amsterdam)
P2.9 The brain’s immune awakening: Investigating microglial changes in stress-susceptible and resilient mice
Laurie Boulesteix (Nijmegen)
P2.10 Dissecting the cellular identity of stress- and reward-responsive ensembles in the ventral tegmental area
Nikoleta Bourtouli (Tilburg)
P2.11 Stress attenuates the excitability of accumbal neurons projecting to the lateral hypothalamus: potential consequences for binge eating
Wenjie Du (Utrecht)
P2.12 The GluN2A contribution to persistent activity in the Prefrontal cortex
Oreoluwa Fakeye (Southampton, United Kingdom)
P2.13 Modulation of network activity by 4-aminopyridine in patient iPSC-derived neurons with CACNA1A genetic variants
Lucas van Grootveld (Nijmegen)
P2.14 The role of sex in sleep loss-induced changes in hippocampal spine density
Sophie Hoogerhuis (Groningen)
P2.15 Tipping the Scales: How differential synaptic vulnerability to amyloid-beta oligomers may underlie network disruptions during early Alzheimer’s disease
Zehra Kazmi (Nijmegen)
P2.16 Structural characterization of microglia-AIS contacts in organotypic slice cultures
Emma Koopman (Utrecht)
P2.17 Computationally-efficient, biologically-informed model of hippocampal oscillatory dynamics
Vitalii Kyzym (Maastricht)
P2.18 Altered intrinsic adaptation explains elevated firing rates in mTORC1-hyperactive neurons under noisy input
Stefan Lip (Rotterdam)
P2.19 Structural synaptic signatures of contextual memory retrieval-reactivated hippocampal engram cells
Panthea Nemat (Amsterdam)
P2.20 Astrocytes and apolipoprotein E: shielding or shattering synapses in Alzheimer's disease?
Bas Ooijman (Nijmegen)
P2.21 Neuropathological changes in the paraventricular nucleus in individuals with type 1 diabetes mellitus
Inês Rodrigues Fernandes (Amsterdam)
P2.22 Photo-uncaging of Pam2CSK4 and Pam2CSTEG induces Toll-like receptor activation
Angelica Sabogal Guaqueta (Amsterdam)
P2.23 Noradrenergic modulation of the perirhinal network
Léa Salette (Amsterdam)
P2.24 Stress and inflammation: effects on human induced pluripotent stem cell-derived microglia
João Lucas de Sousa Peres (Groningen)
P2.25 The role of vacuolar protein sorting 4a (VPS4a) in synaptic proteostasis
Rohit Sundar (Nijmegen)
P2.26 Identifying synaptic substrates of ESCRT-dependent degradation
Devaraj Thittayil Puthusserry (Nijmegen)
P2.27 An imaging pipeline for high-resolution spatiomolecular mapping of CA1 engram cell synapses
Evangelia Tsioutsia (Amsterdam)
P2.28 The role of the kappa-opioid receptors in the nucleus accumbens in the context of stress-related binge-eating behaviour
Zoë van Loenen (Utrecht)
P2.29 Axon Initial Segment structural plasticity and network homeostasis in hIPSC-derived excitatory/inhibitory neurons co-cultures
Noémie Zerrouki (Amsterdam)
P2.30 The role of C9ORF72 in the delivery of newly synthesized lysosomal proteins in neurons
Ilse Bijker (Utrecht)
P2.31 The Rhesus Macaque as a model of aging and neurodegeneration
Loet Coenen (Rijswijk)
P2.32 Bacterial protein Curli as a possible driver of a-synuclein aggregation in Parkinson's Disease
Lousanne de Wit (Utrecht)
P2.33 Drosophila models of histidyl-tRNA synthetase-associated peripheral neuropathy
Mathilde Dijkgraaf (Nijmegen)
P2.34 Dynamical models yield distance to criticality to assess ageing brain dynamics
Bas Drost (Nijmegen)
P2.35 Unravelling the missing link between brain microvessels and microglia in cerebral small vessel disease
Romaysa El Ajjouri (Maastricht)
P2.36 Inhibiting acute episodic neurological decline in vanishing white matter
Karolina Figa (Amsterdam)
P2.37 Neuropathology in post-mortem brain tissue of rhesus macaques 12-months post SARS-CoV-2 infection
Marieke Fortuin (Rijswijk)
P2.38 Common and unique microglial states across neurodegenerative diseases in the human brain
Beáta Gaálová (Groningen)
P2.39 Single-nucleus sequencing in R6/2 mice reveals Huntington’s disease specific cell populations and partial transcriptional normalization by GR antagonism
Max Gentenaar (Leiden)
P2.40 Subtype-specific differentiation of midbrain dopaminergic neurons from hESCs via WNT pathway modulation
Sofia Isaakidou (Naples, Italy)
P2.41 Investigating the role of microglial pathology in familial Alzheimer’s disease using an air-liquid interface corticol organoid model
Poojya Ivatury (Utrecht)
P2.42 Investigating synaptic alterations in C9ORF72-ALS using an air-liquid-interface cortical organoid model
Britt Kwakernaak (Utrecht)
P2.43 Stress-Alzheimer’s nexus: unravelling how stress affects microglial function
Kristel Mulder (Groningen)
P2.44 Exploring Teneurin-4 mutants in Parkinson’s Disease: protein structure and extracellular vesicles
Maja Napieraj (Delft)
P2.45 Morphological and biochemical characterization of myelin from normal-appearing regions in Multiple Sclerosis
Angeles Ocaña Cara (Amsterdam)
P2.46 Development of a bioluminescent reporter to study neuronal secretory autophagy
Stela Papadaki (Utrecht)
P2.47 Cell-specific molecular profiling of patient-derived neuronal cultures in sporadic Alzheimer’s disease
Renzo Riemens (Maastricht)
P2.48 Behavioural effects of early handling in ageing male and female APP/PS1 and WT mice
Eva Ruzicka (Amsterdam)
P2.49 Investigating lysosomal variability in patterned Purkinje cell degeneration
Cam Sawyer (Rotterdam)
P2.50 The effects of an early dietary intervention with ω3 polyunsaturated fatty acids on lipid droplets in APP/PSEN1 mice
Margherita Serafini (Amsterdam)
P2.51 Eyes on the brain: retinal pathology as a biomarker for cerebral amyloid angiopathy
Johannes van der Haas (Nijmegen)
P2.52 Generation and functional MEA characterization of isogenic SCA1 cell lines
Jill Simone Maria van der Kooij (Leiden)
P2.53 The effect of muscle intrinsic toxicity of mutant TDP-43 on the development of ALS-like phenotypes
Hymke van der Zee (Nijmegen)
P2.54 Diesel exhaust particles promote ferroptotic neuronal death and impair microglial function
Leshan Zhang (groningen)
P2.55 Selective activation of TNFR2 as a therapeutic strategy for Alzheimer’s disease
Ilse Zwiers (Groningen)
P2.56 Studying the effects of the CAMK2B-p.P139L mutation in neurodevelopmental disorder using human iPSC-derived neurons
Mirle Buurma (Rotterdam)
P2.57 The molecular basis of neural lineage specification deficits in Rett Syndrome
Tessa Chambon (Utrecht)
P2.58
Investigating neural mechanisms of behavioral inflexibility in the Shank2 knockout mouse model
Mick de Koning (Rotterdam)
P2.59 Sensory processing in Shank2 mutant mice
Morgann Dettingmeijer (Rotterdam)
P2.60 Rescue of disrupted dopaminergic development by lineage-specific HPRT1 reactivation in a genetic mouse model of Lesch-Nyhan Disease
Koen Geelen (Nijmegen)
P2.61 The developmental role of the Crus I lobule and its influence on whole brain morphology and behavioural outcomes
Nathaniel Germain (Rotterdam)
P2.62 Investigating the therapeutic potential of antisense oligonucleotides on SYNGAP1 haploinsufficiency
Deniz Gülyurt (Rotterdam)
P2.63 Precursor activity in 24 hours EEG recordings of children with childhood absence epilepsy
Annika Lüttjohann (Münster, Germany)
P2.64 Characterization of a novel duplication 15q syndrome mouse model
Amy van Hattem (Rotterdam)
P2.65 A bioluminescence-based assay for the screening of antisense oligonucleotides as a therapeutic approach for tuberous sclerosis complex
Margot Zeelenberg (Rotterdam)
P2.66 The role of the Retrosplenial Cortex in stress resilience
Anna Alikhanbeigi (Nijmegen)
P2.67 Modulating alcohol-seeking behaviour in rats: the role of dopamine and serotonin systems
Anna Cabiscol Claveria (Nijmegen)
P2.68 Whole-brain functional connectivity tracks state and symptom severity in depression
Ilan Libedinsky (Amsterdam)
P2.69 Bridging transcriptomics and PTSD: understanding the molecular landscape underlying stress resilience vs. susceptibility
Thibault Merkelijn (Nijmegen)
P2.70 Effects of running on vertical versus horizontal wheels on adult hippocampal neurogenesis in male mice
Femke Niessen (Amsterdam)
P2.71 Chemogenetic manipulation of TH-expressing neurons in the VTA affects hyperactivity in activity-based anorexia model in rats
Jessie Nijman (Bussum)
P2.72 Neuronal activity in the prefrontal cortex in susceptibility versus resilience to stress
Emanuela Pirani (Nijmegen)
P2.73 Ensembles activated during a novel model for binge episodes in anorexia nervosa
Frankie Pulleman (Utrecht)
P2.74 Large-scale meta-analysis of cortical thickness reveals shared brain alterations across ten major neuropsychiatric disorders
Sebastian Quiroz Monnens (Nijmegen)
P2.75 The role of prefrontal cortex D1 receptor neurons projecting to the basolateral amygdala in palatable food intake and impulsive behavior
Atanas Rusenov (Rotterdam)
P2.76 Investigating prefrontal cortical projections of binge ensembles
Luc Sangers (Utrecht)
P2.77 The influence of polygenic risk score for borderline personality disorder on structural and functional measures in unaffected individuals
Mary-Ann van der Linden (Marburg, Germany)
P2.78 Exploring the role of substantia nigra dopamine neurons in anxiety and hyperactivity in anorexia nervosa
Nynke van Walraven (Utrecht)
P2.79 The effect of estrogen on fear conditioning in women: a systematic review and meta-analysis
Sam Vlasman (Utrecht)
P2.80 The interactions between daily physical activity, affect, and depressive symptoms in adolescents remitted from depression and anxiety disorders
Anna Vuuregge (Amsterdam)
P2.81 Uncertainty-modulated prediction error in mouse primary visual cortex
Kevin Hoogers (Bonn, Germany)
P2.82 Uncovering dual pathways for the sense and control of balance through reaction-time analysis
Hil Steketee (Rotterdam)
P2.83 Cell types and priors: Cerebellar encoding of sensorimotor timing
Julius Koppen (Rotterdam)
P2.84 Contribution of sensorimotor load cues to the perception of whole-body orientation during standing balance
Mila Post (Rotterdam)
P2.85 Sensory cue-based fear engram in stress susceptible and resilient mice
Mathilde Beers (Nijmegen)
P2.86 Investigating active avoidance in a mouse model for compulsive behavior
Alfredo Elhazaz Fernandez (Amsterdam)
P2.87 Wake-inducing interaction: a new behavior linked to sleep disruption in a social context in Drosophila melanogaster
Rafaela Gamboa von Groll (Groningen)
P2.88 In vivo microscopy to track the neural substrate for auditory-vocal memory in songbirds
Emily Köhler (Groningen)
P2.89 Stress and food reward but not impulsive action evoke medial prefrontal cortex dopamine release
Karlijn Kooij (Utrecht)
P2.90 Specificity of height and brain volume genetics
Bernardo Maciel (Amstedam)
P2.91 Restoring access to ‘lost’ memories: using vardenafil to reverse sleep deprivation-induced amnesia
Camilla Paraciani (Groningen)
P2.92 “Neural Scars of the Past”. Brain-wide activation profiles associated with early life adversity and their recurrence during adult stress
Myrthe Pluim (Nijmegen)
P2.93 Brain-wide analysis of inaccessible memories after sleep deprivation
Dimitrios Tantis-Tapeinos (Groningen)
P2.94 Approach or avoid? Developing an approach-avoidance motivation conflict task for rats
Sofia Mayz (Amsterdam)
P2.95 Behavioral impact of Mitofusin 2 downregulation in accumbal dopamine receptor D1-expressing medium spiny neurons
Giulia Mozzanica (Groningen)
P2.96 The role of the rat anterior insular cortex in choice between alcohol and social reward
Jan Schoonenberg (Amsterdam)
P2.97 Mapping efferent projections from dopamine D1 and D2 receptor expressing medium spiny neurons of the nucleus accumbens throughout the brain of male and female rats
Salimat Semenova (Amsterdam)
P2.98 From synapse to memory: investigating the role of Dbn1 in engram cell synaptic connectivity
Öznur Bilir (Amsterdam)
P2.99 Investigating Subsequent Memory Effect with fNIRS
Petra Bíró (Tilburg)
P2.100 Investigating the engram specific role of SHANK in memory persistence
Hannah Jehli (Amsterdam)
P2.101 Sex differences in learning rate and performance on a touchscreen-based pattern separation task in rats
Tamar Puttman (Groningen)
P2.102 A new magnetic resonance approach to study processes in neurodegenerative diseases
Martina Huber (Leiden)
P2.103 Modelling brain-to-heart innervation using innovative multi-organ chip technology
Marthe Kaal (Enschede)
P2.104 Providing clarity: A comparative analysis of optical clearing agents for acute and organotypic mouse brain slices
Jessie Kroon (Amsterdam)
P2.105 BCI-sift: an automated feature selection toolbox for brain-computer interface applications
Elena Offenberg (Utrecht)
P2.106 EDEN: A high-performance, general-purpose, NeuroML-based neural simulator
Sotirios Panagiotou (Rotterdam)
P2.107 Towards characterising the phosphoproteome of synapses in memory
Kim Verdaasdonk (Amsterdam)
P2.108 A differentiable, embodied cerebellar model for learning motor control
Lennart Paul Liong Landsmeer (Rotterdam)
P2.109 Intra-operative neurophysiological monitoring in the first week of life
Chagajeg Soloukey (Rotterdam)
P2.110 Early life stress-induced emotional dysregulation is modulated through hypothalamic DNA methylation via methyldonor diet supplementation
Natalia Schilder (Amsterdam)
P2.111 Uncover the underlying mechanisms of AIS plasticity in distinct neuronal types
Ana Rita da Cunha (Amsterdam)
The two poster sessions are scheduled for Thursday, 19 June, at 17:00 and Friday, 20 June, at 16:30.
If your abstract is selected for a poster presentation, when preparing your poster please remember that the maximum area available is 96 x 122 cm (width x height); the poster must have a portrait format. We recommend preparing your poster in a standard A0 size (841 x 1189 mm; width x height).
"Portrait" is fine 
"Landscape" not...
Your poster should be readable from a 2-metre distance; as a rough guideline, use a font size of 72 pts for your title, and a minimum of 28 pts for your text.
Posters must be mounted on the day of the presentation only, between 08:00 and the start of the first session of the day (10:00 on Thursday, and 09:30 on Friday).
Posters must be removed at the end of the day only: 18:45 on Thursday and within 18:30 on Friday. Posters from the Thursday session that are still up by Friday at 08:00 will be discarded by the venue personnel so that the Friday posters can be set up. Posters left behind after the conclusion of the meeting will be discarded by the venue personnel.